AL-803 (B) · Bio Informatics/Official Syllabus
Bio Informatics (AL-803 (B)) - Official Syllabus
1
Unit 1
Introduction
- Introduction to bioinformatics, objectives of bioinformatics
- Basic chemistry of nucleic acids, structure of DNA & RNA
- Genes, structure of bacterial chromosome
- cloning methodology
- Data maintenance and Integrity Tasks
2
Unit 2
Bioinformatics Databases & Image Processing
- Types of databases, Nucleotide sequence databases, Protein sequence databases, Protein structure databases
- Normalization, Data cleaning and transformation
- Protein folding, protein function, protein purification and characterization
- Introduction to Java clients, CORBA, Using MYSQL
- Feature Extraction
3
Unit 3
Sequence Alignment and database searching
- Introduction to sequence analysis, Models for sequence analysis
- Methods of optimal alignment
- Tools for sequence alignment
- Dynamics Programming
- Heuristic Methods
- Multiple sequences Alignment
4
Unit 4
Gene Finding and Expression
- Cracking the Genome, Biological decoder ring
- finding genes through mathematics & learning, Genes prediction tools
- Gene Mapping, Application of Mapping
- Modes of Gene Expression data, mining the Gene Expression Data
5
Unit 5
Proteomics & Problem solving in Bioinformatics
- Proteome analysis, tools for proteome analysis
- Genetic networks, Network properties and analysis
- complete pathway simulation: E-cell
- Genomic analysis for DNA & Protein sequences
- Strategies and options for similarity search
- flowcharts for protein structure prediction
Reference Books
- BIOINFORMATICS with fundamentals of Genomics & Proteomics
- Bioinformatics - Concepts, skills & Applications
- Bioinformatics
- Micrarray BioInformatics
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